Regarding cabin space, the Sierra 1500's interior is thoughtfully designed with the driver's convenience in mind, featuring easily accessible controls and materials that improve with higher trim levels. From the SLE trim upwards, a 12.3-inch digital instrument panel is standard, with premium features like a head-up display and power-adjustable steering column available on higher trims. The pinnacle of luxury, the Denali Ultimate trim boasts open-pore wood trim, extensive leather coverage, and 16-way power-adjustable and massage-capable front seats. It also offers ample storage solutions, though without groundbreaking innovations, including a multifunctional tailgate and a unique, presumably more durable carbon-fiber-reinforced cargo bed.
The Sierra 2500HD and 3500HD models present a large dashboard with intuitive controls, offering a split-folding front bench as standard, with the option to upgrade to bucket seats and a full center console. These models can be enhanced with luxurious options such as a head-up display, heated steering wheel, heated-and-cooled front seats, and wireless charging, ensuring both comfort and convenience across the board.